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Varicella Zoster Virus

Varicella Zoster Virus

Varicella Zoster Virus (VZV) is a double-stranded DNA virus belonging to the Herpesviridae family. It is responsible for causing two distinct clinical conditions: chickenpox (varicella) and shingles (herpes zoster). Chickenpox, primarily affecting children, manifests as a highly contagious illness characterized by a widespread, itchy rash. VZV establishes latency in sensory ganglia following the primary infection. Later in life or during periods of immunosuppression, the virus may reactivate, leading to shingles—a painful, localized rash with a dermatomal distribution. The primary mode of VZV transmission is through respiratory droplets or direct contact with skin lesions. While chickenpox is usually a self-limiting disease, shingles can result in long-term complications such as postherpetic neuralgia. Vaccination, with the Varicella vaccine for chickenpox and the Zoster vaccine for shingles, has proven effective in preventing or reducing the severity of both conditions. Antiviral medications can also be prescribed to manage active infections and alleviate symptoms. Understanding the pathogenesis of VZV, its transmission dynamics, and the complications associated with chickenpox and shingles is crucial for public health initiatives, vaccination strategies, and clinical management. Ongoing research aims to enhance our knowledge of VZV, improving preventive measures and treatment options for individuals affected by these related viral diseases.

Committee Members
Speaker at World Congress on Infectious Disease 2025 - Reza Nassiri

Reza Nassiri

Michigan State University, United States
Speaker at World Congress on Infectious Disease 2025 - Francis J Castellino

Francis J Castellino

University of Notre Dame, United States
Speaker at World Congress on Infectious Disease 2025 - Saurabh Chattopadhyay

Saurabh Chattopadhyay

University of Kentucky College of Medicine, United States
WCID 2025 Speakers
Speaker at World Congress on Infectious Disease 2025 - Johnson J H Wang

Johnson J H Wang

Wang Electro-Opto Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Victor J Alexander

Victor J Alexander

Capital Stem Cell Research Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Jacob R Miller

Jacob R Miller

Penn State University, United States
Speaker at World Congress on Infectious Disease 2025 - Anmol Grewal

Anmol Grewal

Abrazo Health, United States

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