Training program established by the Institutional Committee for the Care and Use of Laboratory Animals (IACUC) in pre-clinical trials on infectious diseases
Mario Enrique Garcia Rodriguez, Institute of Tropical Medicine Pedro Kouri, Cuba
The implementation in our institution, Regional Reference Center for the study of Tropical Diseases, of the Institutional Committee for the Care and Use of Laboratory Animals (IACUC), meant a change in the institutional approach in research with laboratory animals due to the need to respect the welfare of animals in the study of preclinical researc [....]
New technologies using blood immune cells in inform on human disease status
John J Miles, James Cook University, Australia
The human immune system is a hugely complex network of cell types relentlessly communicating on host health through direct recognition and secreted compounds. We have recently found that listening to this immune cell “chatter” through phenotyping or molecular typing can inform pathology in rapid time using high-dimensional analysis and [....]
Combined Tuberculosis/HIV infection in Russia: Current status and perspectives
Erzheny Tsybikova, Federal Research Institute for Health Organization, Russia
Objective: Epidemiology of combined TB/HIV infection in the Russian Federation over the past 10 years (2009-2018). Materials and methods: retrospective analysis of statistical data received from the reporting forms of the ROSSTAT and MoH of Russia for the period (2009-2018). For the analysis, cartographic and correlation analyses were used. R [....]
Potential for spread of Leishmania tropica in southern Europe by local sand flies
Petr Volf, Charles University, Czech Republic
Various Leishmania species constitute an important global health problem with millions of people affected. Leishmania tropica is the causative agent of cutaneous leishmaniases (CL) in the Old World, occurring in many countries of Asia and Africa. Currently, a great concern is posed by outbreaks of CL in the Middle East, connected with people displa [....]
Cutaneous Myiasis in an Elderly Man
Berna bozca, infectious diseases specialist, Turkey
Myiasis is the parasitic infestations of live human and other vertebrate animals with dipterous larvae feeding on the host’s dead or living tissues, liquid body substances. Diagnosis of myiasis depends on the demonstration of larvae on the host’s tissues. Myiasis is classified according to the affected location and the association betwe [....]
Sepsis as a metabolic adaptation failure
Claude Libert, Center for Inflammation Research, Belgium
Sepsis is a most deadly unmet medical need. It hits 30 million people yearly, leading to 8 million deaths, amongst which 3 million children. Usually, sepsis starts with a serious (bacterial) infection that spreads and triggers many systems of the host, including inflammation, immunity, coagulation, complement, but also thermoregulation, circadian r [....]
Predictors of all-cause mortality in TB in a Malaysian University Tertiary Hospital
Sarah Choo Qian Rou, University of Malaya, Malaysia
Malaysia is classified as a Tuberculosis (TB) intermediate burden country. As TB is a notifiable disease in Malaysia, we ought to collect more complete information regarding region specific TB data in our country. The aim of the study is to determine the treatment outcome and associated predictors of all-cause mortality in TB patients in a Malaysia [....]
THE RELATIONSHIP BETWEEN SPLENOMEGALY AND LUNG INVOLVEMENT PATTERNS AND SEVER?TY SCORE IN COVID-19 PNEUMONIA
Yusuf Aksu, Yunus Emre State Hospital, Turkey
The new type of Coronavirus disease 2019 (COVID-19) is a viral infection and has spread all over the world in a short time and has been defined as a pandemic. Computed Tomography has a key role in the diagnosis and follow-up of this disease. In this study, we aimed to compare the frequency of lung involvement patterns and total lung severity score [....]
Management and Outcome of Tetanus in a Tertiary Hospital in Albania
Entela Kolovani, University Medical Center of Tirana Mother Teresa, Albania
Despite improving the vaccination policy especially during last decade in Albania, still there were tetanus cases reported, whose occurrence is strongly related to two major factors: the decrease of IgG antibody concentrations toward the disease with increasing age (the mandatory vaccination in Albania ends by 18 years old) and improper treat [....]