Title : Conserved Antisense RNAs Significantly Inhibit Pan-Coronaviruses
Abstract:
The continuing pandemics of severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and novel coronavirus disease 2019 (COVID-19) underscore the urgent need for the development of anti-pan-coronavirus drugs that can target emerging coronaviruses and their variants. Despite this pressing need, there is currently no experimental report effectively targeting pan-coronaviruses. In response to this challenge, we have invented a novel strategy employing conserved antisense RNAs against pan-coronaviruses (CAR-pCoV). The promising results of our study will be presented orally during the conference.
