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WCID 2025

Increased incidence of nontyphoidal salmonella infections following COVID-19 outbreak: Is it an impact of the pandemic?

Kundoly Velayudhan Suseela, Speaker at Infectious Disease Conference
Amala Institute of Medical Sciences, India
Title : Increased incidence of nontyphoidal salmonella infections following COVID-19 outbreak: Is it an impact of the pandemic?

Abstract:

Infection by Nontyphoidal Salmonella (NTS) is considered a zoonotic food poisoning of animal and poultry origin.NTS gastroenteritis is a major cause of diarrheal illness worldwide, which is usually self-limiting. NTS can also cause extraintestinal manifestations and serious complications such as septicemia, particularly in very young, elderly, and immunocompromised patients. Following the relaxation of the COVID-19 Outbreak lockdown, in a tertiary care centre, admissions of NTS infection showed a two-fold rise compared to pre-COVID years.

We examined 2312 and 937 stool samples collected during the pre-COVID and post-COVID outbreak period, respectively. The number of samples collected during the outbreak (2020) was 273. During the pre-COVID-19 period (2015–2019), the average annual isolation rate of NTS was 5.63%. During the lockdown of 2020, the corresponding rate was 5.49%. The isolation rate showed a significant rise (11.45%) during the relaxation of the lockdown (P < 0.001). No significant change in resistance to antibiotics other than ciprofloxacin was noted. Malignancy was the leading comorbid condition (11.91%) followed by chronic liver diseases (10.31%).

The role of CD4 deficiency leading to NTS infection is well known. The long term impact of COVID-19 infection in the immune system leading to NTS diarrhea and septicemia should be studied in detail.

Biography:

Dr. K V Suseela  graduated from Gov. Medical College , Thrissur, Kerala, India and received MD degree in Microbiology from Govt. Medical College, Kozhikode, Kerala, India. Currently, she is working as Professor and Head of Microbiology department, Amala Institute of Medical Sciences, Thrissur, Kerala, India. She had published more than 20 research articles in peer reviewed national and International journals. Prof. Dr. Suseela has keen interest in bacteriology research.

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