Title : FAST nanotechnology and its practical applications

Abstract:

FAST (Facilitated Self-Assembling Technology) is a powerful nanotechnology that enhances the effectiveness of hydrophobic molecules in aqueous formulations. Unlike traditional nanotechnology, FAST requires only one or two water-miscible organic solvents to form stable nanoparticles from lipid-soluble compounds without engineering procedures or additives. Numerous drugs and drug candidates with poor solubility and bioavailability can self-assemble into highly hydrophilic and stable nanoparticles using FAST. This presentation highlights practical applications of EC16 (Epigallocatechin-3-Gallate-Palmitate, or EGCG-palmitate) nanoparticles in disease control and prevention, demonstrated by prototypes of nasal sprays, oral rinses, skin disinfectants, and a norovirus drug candidate. Results indicate that FAST significantly amplifies the antimicrobial activity of EC16, showcasing its potential to revolutionize drug development, enhance the efficacy of existing drugs, and dramatically reduce manufacturing costs.

Biography:

Dr. Stephen Hsu earned a Ph.D. degree from University Cincinnati College of Medicine. He joined Memorial Sloan-Kettering Cancer Center as a Research Fellow and served as a lecturer in the National University of Singapore. He is currently a tenured professor at Dental College of Georgia, Augusta University. Dr. Hsu invented several technologies and products to treat various diseases and conditions such as xerostomia and viral infections based on results from phase II clinical trials. Dr. Hsu’s NIH support is on novel virucidal disinfectants against bacterial spores, and nasal nano-drug intervention on Long COVID associated neurologic symptoms.