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Tetanus

Tetanus

Tetanus, caused by the bacterium Clostridium tetani, is a potentially severe and life-threatening condition characterized by muscle stiffness and spasms. The bacterium produces a potent neurotoxin known as tetanospasmin, which interferes with neurotransmission, leading to uncontrolled muscle contractions. Tetanus spores are commonly found in soil and can enter the body through wounds, cuts, or abrasions. The clinical features of tetanus include trismus (lockjaw), muscle stiffness, difficulty swallowing, and rigidity of neck muscles. As the disease progresses, generalized muscle spasms can occur, potentially leading to respiratory failure. Tetanus is a medical emergency that requires prompt intervention. Prevention of tetanus primarily involves vaccination with the tetanus toxoid. The vaccine is often administered as part of the combination vaccine DTaP/DT/Td, protecting against diphtheria, tetanus, and pertussis. Booster doses are recommended every 10 years or after certain injuries to maintain immunity. Proper wound care, including cleaning and disinfection, is also crucial in preventing tetanus, especially in individuals with incomplete or unknown vaccination histories.

Committee Members
Speaker at World Congress on Infectious Disease 2025 - Reza Nassiri

Reza Nassiri

Michigan State University, United States
Speaker at World Congress on Infectious Disease 2025 - Francis J Castellino

Francis J Castellino

University of Notre Dame, United States
Speaker at World Congress on Infectious Disease 2025 - Saurabh Chattopadhyay

Saurabh Chattopadhyay

University of Kentucky College of Medicine, United States
WCID 2025 Speakers
Speaker at World Congress on Infectious Disease 2025 - Johnson J H Wang

Johnson J H Wang

Wang Electro-Opto Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Victor J Alexander

Victor J Alexander

Capital Stem Cell Research Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Jacob R Miller

Jacob R Miller

Penn State University, United States
Speaker at World Congress on Infectious Disease 2025 - Anmol Grewal

Anmol Grewal

Abrazo Health, United States

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