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Smallpox

Smallpox

Despite its eradication, smallpox remains a subject of concern due to its potential use as a bioweapon. The variola virus is classified as a Category A bioterrorism agent, prompting ongoing research to improve preparedness and response strategies. Stockpiles of the smallpox vaccine are maintained for emergency use, and research explores novel antiviral treatments and vaccination approaches. The legacy of smallpox research extends beyond eradication efforts. The study of the variola virus and related poxviruses contributes to our understanding of viral pathogenesis, immunology, and vaccine development. Poxvirus research has implications for broader vaccine design and antiviral strategies against related pathogens. Post-eradication challenges include the secure handling and storage of remaining variola virus stocks, located in designated repositories in the United States and Russia. The debate over the destruction of these stocks continues, weighing concerns about accidental release or deliberate misuse against the benefits of retaining the virus for research purposes.

Committee Members
Speaker at World Congress on Infectious Disease 2025 - Reza Nassiri

Reza Nassiri

Michigan State University, United States
Speaker at World Congress on Infectious Disease 2025 - Francis J Castellino

Francis J Castellino

University of Notre Dame, United States
Speaker at World Congress on Infectious Disease 2025 - Saurabh Chattopadhyay

Saurabh Chattopadhyay

University of Kentucky College of Medicine, United States
WCID 2025 Speakers
Speaker at World Congress on Infectious Disease 2025 - Johnson J H Wang

Johnson J H Wang

Wang Electro-Opto Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Victor J Alexander

Victor J Alexander

Capital Stem Cell Research Corporation, United States
Speaker at World Congress on Infectious Disease 2025 - Jacob R Miller

Jacob R Miller

Penn State University, United States
Speaker at World Congress on Infectious Disease 2025 - Anmol Grewal

Anmol Grewal

Abrazo Health, United States

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