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Nipah Virus Disease

Nipah Virus Disease

Nipah virus (NiV) is a zoonotic virus belonging to the Paramyxoviridae family. The natural reservoir for Nipah virus is believed to be fruit bats of the Pteropodidae family, particularly those of the Pteropus genus. Transmission to humans occurs through direct contact with infected bats, consumption of contaminated fruits or date palm sap, or close contact with infected animals, particularly pigs. Clinical features of Nipah Virus Disease (NiV) range from asymptomatic infection to severe respiratory and neurological symptoms. The incubation period is typically 4 to 14 days, with initial symptoms resembling influenza, including fever, headache, and muscle pain. Severe cases progress to encephalitis, characterized by altered mental status, seizures, and focal neurological deficits. Respiratory symptoms such as cough and breathing difficulties may also occur. Nipah virus has caused several outbreaks in South and Southeast Asia, with sporadic cases reported in Bangladesh and India. The case fatality rate can be high, ranging from 40% to 75%, emphasizing the significance of early detection, isolation, and supportive care.

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