Saurabh Chattopadhyay, University of Kentucky College of Medicine, United States
The interferon (IFN) system is a critical first-line defense against viral infection, orchestrating antiviral programs while shaping early inflammatory responses. Although inflammation is essential for pathogen control, dysregulated cytokine production is a major driver of morbid [....] » Read More


Title : The impact of expanded adolescent vaccination against Omicron waves depends on the epidemic status: A mathematical modelling study
Anna Fairweather, University of Oxford, United Kingdom
Background: Deployment of effective vaccination against the various SARS-CoV-2 variants was crucial for controlling the spread of COVID-19. These retrospective modelling analyses evaluated the impact of the expanded adolescent COVID-19 vaccination in England at two different epid [....] » Read More
Title : Comprehensive HIV care through integrated STI and primary care services at the LGBTQ+ Center of Southern Nevada
Darya V Fridman, The Southern Nevada LGBTQ+ Center, United States
Sexually transmittied infections (STIs), including HIV and viral hepatitis, often present with minimal symptoms, contributing to ongoing transmission and delayed treatment. Early diagnosis and consistent engagement in HIV and STI care are critical, particularly among underserved [....] » Read More
Title : Meeting the needs of adults aged 50+ with HIV through the new opening of a primary care clinic at the LGBTQ Center of Southern Nevada
Darya V Fridman, The Southern Nevada LGBTQ+ Center, United States
Aging individuals living with HIV face distinct challenges, including managing comorbidities, maintaining continuity of care, and sustaining adherence to treatment. The LGBTQ Center of Southern Nevada provides integrated HIV services through its downtown STI clinic and newly open [....] » Read More
Title : Camostat-polysaccharide dual-action nasal spray for mucosal barrier-driven prevention of viral infections
Yujeong Na, Daewoong Pharmaceutical Co., Ltd, Korea, Democratic People's Republic of
Antiviral activity was demonstrated in human nasal epithelial cells and a mouse influenza model. The formulation inhibited viral entry in vitro and suppressed TMPRSS2 expression in vivo, a key factor for viral penetration. Cytotoxicity tests confirmed no toxicity, following ISO 1 [....] » Read More