Microbial Biogeochemistry plays a crucial role in the study of antimicrobials, exploring the interactions between microorganisms and the geochemical processes involved. Microbes, both beneficial and pathogenic, contribute significantly to the biogeochemical cycling of antimicrobials in various environments. Understanding the microbial dynamics in antimicrobial-rich ecosystems is vital for comprehending the impact of antimicrobial substances on microbial communities and their broader ecological implications. This field delves into microbial resistance mechanisms, adaptation strategies, and the influence of microbial activities on the fate and transport of antimicrobials in diverse settings.