Title : Prevalence and resistance profile from ESKAPE bacteria group in a third level hospital
Bacterial infections are worldwide problem health. Bacterial infections are described as the proliferation of harmful bacteria on or inside the body. There is a long list of infections among pneumonia, meningitis, sexually transmitted, bacterial skin infections, respiratory infections or nosocomial infections. Nosocomial infections or healthcare-associated infections occur in patients under medical care. Infections occur worldwide in developed and developing countries. Nosocomial infections are a problem health worldwide since they present high rates of antibiotic resistance which affects treatment. Nosocomial infections increase prolonged hospital stay, long term disability, and increased mortality rate.
Distribution of sites of nosocomial infections is a catheter, bacteremia, respiratory tract, urinary tract, skin and soft tissue, surgical site and lower respiratory tract. Many different pathogens may cause nosocomial infection. The infecting organisms vary among the patient population, healthcare system, and countries. Bacteria are the predominant microorganisms that are associated with nosocomial infections. Bacteria can present high rates of resistance due to plasmid transference thus description of resistance bacteria among the countries are important since we can have epidemiological values to prevent these rates increasing.
Nosocomial infections are caused by the ESKAPE bacteria group, which is an acronym for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. Persistence use of antibiotics has provoked the emerge of multidrug-resistant (MDR) and extensively drug resistance (XDR) for those whose effective drugs are limited. Extended-spectrum β-lactamase (ESBL) and carbapenemase-producing Gram-negative bacteria are an important therapeutic challenge. Thus, the search of novel therapeutics to treat drug-resistant infections is a matter who must be handled for researchers over the world.