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Potential speaker for Infectious Diseases conferences 2020
Sayed farouk mohamed
University of Al-Azhar, Egypt
Title : Diagnostic role of cerebrospinal lactate dehydrogenase and serum procalcitonin in meningitis in beni-suiefe governorate

Abstract:

Background: Meningitis means the membranes that cover the brain, spinal cord, and the intervening cerebrospinal fluid becomes inflamed  as a result of  infection of cerebrospinal fluid by a variety of infectious agents. Acute meningitis is caused by a variety of infectious agents. The most serious form is caused by pyogenic bacteria, such as S.pneumonia, N.meningitides, and H.influenza.

Aim of  The work: The primary objective of the present study was to assess the diagnostic role of cerebrospinal LDH serum procalcitonin (PCT-Q) in meningitis in Beni- suief governorate and for differentiating Septic from Aseptic meningitis.

Methods: In this Prospective study evaluation of the diagnostic role of cerebrospinal LDH serum procalcitonin (PCT-Q) in meningitis in Beni- suief governorate and for differentiating Septic from Aseptic meningitis  They were divided into four groups: septic meningitis  (Group  I),  Aseptic meningitis  (Group  II), and meningism  (Group  III)  and 100 control cases who were attending fever hospital for other complain than CNS infection from where blood samples were taken to test S. protein, S .LDH and S.procalcitonin.

Results: it  was found that 139 ( 100 %)  of  139 of cases were  above normal range  elevated serum LDH  in septic meningitis  . while  102( 98 %)  of 104 cases were show above normal range elevated serum LDH, while  2 ( 2 %) of  104 cases showed below normal range in Aseptic meningitis group . all cases of meningism show normal range. only 2 control cases were showed

 S.LDH above normal and they have complained of chest infection (pneumonia ).also, it was found that S. PCT  testing was positive in all patients with septic meningitis while  S.PCT testing is positive in 35 patients (34%)  with Aseptic meningitis and negative in 69 patients (66%). And S. PCT-Q testing was negative in all patients with meningism. Also, all control cases were assessed as normal S.PCT level

Biography:

Sayed Farouk Mohamed MD, an assistant professor of Tropical medicine at the University of Al-Azhar, Egypt. He is a consultant of hepatogastroenterology and infectious diseases at the ministry of health hospitals. He published no. of articles in many local journals.

 

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