Title : Zelsuvmi: A promising treatment for molluscum contagiosum
Abstract:
Molluscum contagiosum is a fairly common skin infection in children and immunocompromised adults. It is caused by a poxvirus and causes single or multiple raised, pearl-like lesions (papules). It is a highly contagious and can spread via skin-to-skin contact or on contact with infected article.Treatment modalities for Molluscum are cryosurgery, in-clinic curettage or pulsed dye laser ablation. In early 2024, Berdazimer topical gel was approved for the topical treatment of Molluscum Contagiosum.This review explores Berdazimer topical gel, 10.3% (ZELSUVMI*™), a novel first-phase drug, emerging as a potential game-changer in the treatment landscape of Molluscum Contagiosum due to its unique mechanism of action as a nitric oxide (NO)-producing topical agent and its antiviral properties which presents with compelling evidence of efficacy.
NO is naturally produced by the human body and has various functions including immune defence.It acts as an antimicrobial and affects apoptosis, immunomodulation, cytokine production, and inflammation.The implications of this article extend beyond clinical practice, influencing future research, and prevention strategies. By accentuating the pivotal role of Berdazimer in Molluscum Contagiosum treatment, this review aims to propel the discussion and review on use of innovative therapies and their transformative impact on dermatological care.
Audience Take Away:
Dermatologists, pediatricians, and other healthcare professionals can use this information to diagnose and treat MC in their patients. Parents and caregivers can use this information to learn more about MC and how to care for a child with the infection. This information can help healthcare professionals to better diagnose and treat MC, which can improve patient outcomes. This information could be used by other faculty to expand their research or teaching on MC. For example, a faculty member could use this information to develop a new course on pediatric dermatology. This research does not provide a practical solution to a problem that could simplify or make a designer's job more efficient. This research is not relevant to design. This information can help to raise awareness of MC and improve public health.
