Title : Next-generation proteomics for increased access to infectious disease testing for both human and animal health
Abstract:
Global access to accurate diagnostics for infectious diseases remains a critical challenge, particularly in low-resource settings. Access to accurate, sensitive infectious disease testing, is especially important in managing population health, epidemics and pandemics that have major health economic impacts. Affordable and accurate testing is crucial for improving healthcare access and reducing the global burden of infectious diseases. Traditionally, the most affordable testing is based on a single analyte, often requiring follow-up or reflex testing to rule out causative agents. However, multiplexing enables testing for multiple diseases (diagnostic breadth) or detecting disease at various stages (diagnostic depth) in a single test with a streamlined workflow, thereby increasing diagnostic yield.
Pictor has developed an advanced ELISA-based proteomics platform aimed at delivering precise and efficient diagnostic solutions for complex and infectious diseases in both animal and human health. This platform significantly boosts productivity by incorporating multiple antigens or antibodies into each well of a 96-well plate, delivering comprehensive diagnostic information in less than 2.5 hours from multiple specimen types, including saliva. Analytical performance data from several human infectious disease panels, including HIV/Hepatitis panel, Dengue/Zika panel, and SARS-CoV2 will be discussed. In addition, data from extensive validations of Mycoplasma bovis for animal health will also be presented.
The presentation will highlight the flexibility of the platform for applications spanning research, clinical diagnostics, to epidemiological surveillance, and as a robust tool for improving health economic outcomes and the global burden of infectious diseases.
Audience Take Away:
- They will learn about a new technology to assist with their research or other applications for infectious diseases in humans and animals
- It will provide them with information about a more productive tool and ideas for how they may be able to multiplex their biomarker testing
- Other faculty could use this research to expand their research or teaching, as it also highlights information about non-traditional specimen types
- It provides a practical solution
- It will provide new information with the potential to better address a problem
- Opportunities to accelerate research through an affordable proteomics solution
