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WCID 2023

Silvia Giono Cerezo

Silvia Giono Cerezo, Speaker at Infectious Diseases Conference
National Polytechnic Institute, Mexico
Title : Gram-negative ESKAPE bacteria bloodstream infections in patients during the COVID-19 pandemic in a mexican hospital


Bloodstream infections due to bacteria are a highly consequential nosocomial occurrences and the organisms responsible for them are usually multidrug-resistant. The aims of this study were to describe the incidence of bacteremia caused by Gram-negative ESKAPE bacilli during the COVID-19 pandemic and characterize the clinical and microbiological findings including antimicrobial resistance. A total of 115 Gram-negative ESKAPE isolates were collected from patients with nosocomial bacteremia (18% of the total bacteremias) in a tertiary care center in Mexico City from February 2020 to January 2021.

The most frequently isolated bacteria were Acinetobacter baumannii (34%), followed by Klebsiella pneumoniae (28%), Pseudomonas aeruginosa (23%) and Enterobacter spp (16%). A. baumannii showed the highest levels of multidrug-resistance (100%), followed by K. pneumoniae (87%), Enterobacter spp (34%) and P. aeruginosa (20%). The blaCTX-M-15 and blaTEM-1 genes were identified in all beta-lactamresistant K. pneumoniae (27), while the blaTEM-1 was carried in 84.6% (33/39) of A. baumannii isolates.

Audience Take Away:

  • Audience Microbiologist, Infectious diseases specialists PROTOCOL experience in this hospital during COVID-19 Pandemic time expand their research or teaching and coordination to find microbiological findings including antimicrobial resistance and role of multidrug-resistant Gram-negative ESKAPE bacteria causing bacteremia in nosocomial settings. Could provide new information to assist in a design problem during this research work.



Dr. Silvia Giono Cerezo studied PhD at Instituto Politécnico Nacional. ENCB since 1967 and work there as full time Professor. She joined research group of Dr. Alcantar Curiel at 1Unidad de Investigación en Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México. Ciudad de México, México, to collaborate on Gram-negative ESKAPE bacilli and role of multidrug-resistant consisted in impulse graduate students on Master and PhD to obtain experience on microbiological methods and work together with people with great experience in this area at Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Ciudad de México, México. We have several publications.


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