Title : Gram-negative ESKAPE bacteria bloodstream infections in patients during the COVID-19 pandemic in a mexican hospital
Abstract:
Bloodstream infections due to bacteria are a highly consequential nosocomial occurrences and the organisms responsible for them are usually multidrug-resistant. The aims of this study were to describe the incidence of bacteremia caused by Gram-negative ESKAPE bacilli during the COVID-19 pandemic and characterize the clinical and microbiological findings including antimicrobial resistance. A total of 115 Gram-negative ESKAPE isolates were collected from patients with nosocomial bacteremia (18% of the total bacteremias) in a tertiary care center in Mexico City from February 2020 to January 2021.
The most frequently isolated bacteria were Acinetobacter baumannii (34%), followed by Klebsiella pneumoniae (28%), Pseudomonas aeruginosa (23%) and Enterobacter spp (16%). A. baumannii showed the highest levels of multidrug-resistance (100%), followed by K. pneumoniae (87%), Enterobacter spp (34%) and P. aeruginosa (20%). The blaCTX-M-15 and blaTEM-1 genes were identified in all beta-lactamresistant K. pneumoniae (27), while the blaTEM-1 was carried in 84.6% (33/39) of A. baumannii isolates.
Audience Take Away:
- Audience Microbiologist, Infectious diseases specialists PROTOCOL experience in this hospital during COVID-19 Pandemic time expand their research or teaching and coordination to find microbiological findings including antimicrobial resistance and role of multidrug-resistant Gram-negative ESKAPE bacteria causing bacteremia in nosocomial settings. Could provide new information to assist in a design problem during this research work.
