Title : Rare atypical manifestations of type 2 lepra reactions-A case series
Abstract:
Type 2 lepra reaction can present clinically in varied forms.Ulcers with maculo-papular rash,tender erythematous nodules are an unusual presenting feature of leprosy. They occur as result of neuropathy, type-2 lepra reaction or Lucio's phenomenon. The hall mark of type-2 reaction is erythema nodosum. Very rarely it manifests as ulcerative skin lesions. We describe a case series of 5 patients of type 2 lepra reaction .
Introduction: Leprosy is a multi-organ infectious disease affecting mainly the skin and the nerves. Leprosy is also associated with type-1 and type-2 reactions [1]. When severe, it can rarely manifest as ulcerative skin lesions (erythema necroticans). Ulcers are an uncommon presentation of leprosy. These occur as a result of loss of sensation (peripheral) or very rarely in lepra reaction (both type-1 and type-2 reaction) and are the presenting features of Lucio's phenomenon [1, 2].
Discussion
Skin lesions commonly are macules patch, and plaques, rarely papules or nodules.We presented case series of five patients with varied manifestations of type II lepra reactions because it is important for us to be aware of various manifestations of leprosy including some unusual ones in lepra reactions.
