Title : New technologies using blood immune cells in inform on human disease status
The human immune system is a hugely complex network of cell types relentlessly communicating on host health through direct recognition and secreted compounds. We have recently found that listening to this immune cell “chatter” through phenotyping or molecular typing can inform pathology in rapid time using high-dimensional analysis and machine learning. We are currently developing highly sensitive and specific immune signatures for diagnostics, prognostics and identifying individuals at high risk of disease. In this talk I will describe the work we have achieved thus far across a number of infectious (mycobacteria) and chronic disease (COPD).