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Potential speaker for Infectious Diseases conferences 2020
Silvia Giono Cerezo
National Polytechnic Institute, Mexico
Title : Infections caused by antibiotic-resistant ESKAPE group in Mexico

Abstract:

Infections caused by antibiotic-resistant ESKAPE group microorganisms possess high risk to patients' lives, because  treatment is limited to few therapeutic options. The resistance mechanisms are: production of Extended Spectrum Lactamases (BLEE), Carbapenemes type MBL, enzymatic production of aminoglycoside resistance (HLRA), resistance to vancomycin and methicillin by modification of target site. In Mexico, epidemiological surveillance as well as control and prevention measures are regulated for the control and prevention of nosocomial infections. The American Society of Infectious Diseases (IDSA) defined a group of bacteria included in the term ESKAPE: Enterococcus faecium resistant to vancomycin (ERV), methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella  pneumoniae  with expected -extended spectrum lactamic (BLEEs), Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species, as high-priority pathogens, for representing relevant clinical or public health problems, as well as being very hard therapeutic alternatives.

In this talk I would like to present experiences and work of ours staff group and some other groups have done in Mexico, where the ESKAPE group is already being studied. The audience will be able to learn what methods we suggest to detect BLEEs, AmpC production by inhibition with fenil-boronic-acid and how to be confirmed by PCR assay. Metallo-β-lactamases-(MBL) phenotype production determined by disk diffusion with EDTA. Genes blaKPC, blaVIM, blaIMP, blaNDM and blaOXA-24-like with PCR and efflux pumps using inhibitor of efflux pumps CCCP. Clonality analysis by PGE dissemination in all floors of hospitalization. Our knowledge help to understand the accuracy of results and provide information to assist and resolve similar problems and stablish prevention methods as hand washing.

Biography:

Dr. Silvia Giono Cerezo. Studied Microbiology Ph.D. at Escuela Nacional de Ciencias Biológicas. Instituto Politécnico Nacional. México. The research group now as Full time Professor. Titular member of the National Academy of Medicine. Ex-President Asociación Mexicana de Microbiología. Founder Member, AMIMC, Mexico. Fellowship SLC Utah Univ  Posdoctoral Host at CDC and Emory University. OPS-Latinoamerican Member of Cholera Outbreak. Health Dept INDRE.   Head of Microbiology group. She has published more than 30 research articles in SCI(E) journals.

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