Title : The main reservoir of viruses hidden in carriers is in the intestinal tract, where vaccines do not work.
Abstract:
Every virus is a parasite that cannot exist on its own and is fully dependent on its carrier. The parasite must have its host, and thus is a living cell. Based on the obtained results, it can be assumed that the following could be the most suitable carriers of the virus: bacteria, yeast or other single-cell organisms. Based on work with bovine leukosis virus (BLV), was concluded that a bacterial cell can be the host of the virus. We tested this assumption and confirmed the results. This idea was then tested on the HIV model and we have been able to prove that its host may be bacteria, which was confirmed at the level of DNA as well as proteins.
It is generally accepted that the HIV was transferred to humans from contact with monkeys about 70 to 100 years ago. However, this claim has not been sufficiently confirmed. The spread and incubation period and other symptoms of the Black Death have led to the theory that epidemic may have been caused by hemorrhagic viruses. On the base of our results, we have concluded that the bacterium Yersenia pestis was an infectious agent in the epidemic, together with another agent which we suggest was HIV. Our considerations are strongly supported by the CCR5 delta 32 mutation, which protects against HIV infection and has been present in the Caucasian population for over 2000 years. The plague resulted in a reduction in the number of HIV carriers and an increase in the number of CCR5D32 mutations in the Caucasian population to 10% to 20%. In sub-Saharan Africa, this epidemic and the subsequent sanitation process did not take place, what explains the absence of the CCR5D32 mutation. This results in a much higher level of HIV genetic information in this population.
After overcoming HIV infection by a conventional drug-based treatment approach such as HAART , the infection is suppressed, but there is no evidence that HIV-infected people have been completely free of the virus after HAART therapy. The reason is the existence of reservoirs in which the virus cannot be destroyed. According to our results, the main reservoir of BLV and HIV located in carriers is in the gastrointestinal tract. This is the reason why so far there is no vaccine that would completely rid the infected person of the virus, because no vaccine in the intesrinal tract has an effect on HIV hidden in the carrier.
By destroying microbes – bacteria, yeast, or other single-celled organisms – carrying the virus, the virus ceases to exist. This is how we can stop the majority of viral infections and epidemics.
